Five weeks of roadworks get underway on the Mountain Road later.
The section between Brandywell and the Creg-ny-Baa will shut at 9.30am.
The Department of Infrastructure says it needs to install culverts for drainage and resurface part of the route.
Access to the Victory Café and the summit of Snaefell is being maintained via Tholt y Will and Beinn y Phott road.
Illegal immigrant turned back at Manx border can't stay in UK
Bank scammers warning as calls target Island residents
Island to extend UK VAT cut on power, says Treasury Minister
Woman thanks mystery van driver after daring sea rescue
Stay off damaged slipway in Laxey, says local authority
MHK sues attorney general and returning officer over election votes
Islanders reminded to keep challenging domestic abuse beyond October