From next month only postal services will be available at the Spar on Westmoreland Road in Douglas.
The Isle of Man Post Office says it's due to the ending of the government’s MiCard contract in December, and the digitising of driving and vehicle licensing.
Bill payments and foreign currency exchange will also no longer be available from the branch, as part of changes to take effect from Thursday, September 4.
Parcel collections will still be offered, but for non-postal services people will now have to go to the nearest post-office on Strand Street instead.
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