Improvements to a stream that runs through Pulrose will mean road closures for up to 12 weeks.
The Department of Infrastructure says it needs to prepare culverts for Farmhill Stream, which runs under Groves Road to the River Dhoo.
The DOI says flood risks show work's needed to prevent flooding at the National Sports Centre in extreme weather events.
As a result, part of Groves Road will close on November 7 and reopen when the work is finished at the end of January.
New ministerial post created by chief minister
Huge floating book fair to arrive in Douglas next month
Stay safe for Hop Tu Naa tonight
Special Olympics fundraiser needs you
Peel ready for bonfire and fireworks later
Government: "UK never told us about child murderer"
Farm shop's newest worker needs your name suggestions
Bus Vannin gives update on staffing problems and routes affected today