Police say the Poortown Road in Peel will remain shut until around 7pm tonight after a crash earlier.
Earlier, officers said a crash had closed roads around Tynwald Hill.
They're currently on the scene dealing with the incident.
An emergency Road Closure Order means the route will stay closed between the Switchback Road, Ballig Bridge, and Glen Mooar Road.
Peel ready for bonfire and fireworks later
Peel kicks off the Island's bonfire night fun tonight with its fireworks display.
Government: "UK never told us about child murderer"
The government says it'll write to the UK demanding to know how a convicted child murderer ended up living on the Isle of Man.
Farm shop's newest worker needs your name suggestions
A farm shop in Glen Helen is asking you to name its newest member of staff.
Bus Vannin gives update on staffing problems and routes affected today
Bus Vannin has revealed more details about buses which may not run today.
Toilets vandalised for fourth time in a month
Commissioners in the west of the Island are appealing for help catching those who vandalised toilets this week.
Poppy gets fur-ever home after sparking rescue operation in Douglas
A tiny Manx kitten who was rescued in Douglas city centre has been given a happy ending.
Council gets eight complaints about James Brown in six months
Douglas Council says a newly-built block of flats in Willaston has seen eight reports of antisocial behaviour in the six months since tenants moved in.
More bus staffing problems this weekend
Bus Vannin is warning of more problems with its services this weekend.
