Police say the Mountain Road is currently shut while emergency services deal with several incidents.
The entire route is closed, from Ramsey Hairpin to the Creg-Ny-Baa.
The announcement was made around 5.15pm this evening, Thursday, May 28.
No time has been given for when it's expected to re-open.
Manx Care urges TT fans to check travel insurance
Manx Care has issued advice to bikers coming to the Island for TT.
Over 25 percent still haven't completed censuses
The government says more than a quarter of the Island still haven't filled in their census forms.
Warning for paddleboarders after incidents in wind
The coastguard's urging people to be safe after a number of incidents where paddleboarders got into difficulty in strong winds yesterday, Wednesday, May 27.
TT organisers confirm death of rider Daniel Ingham
TT organisers have confirmed Daniel Ingham was killed in the incident at Doran's Bend during qualifying yesterday.
'No further comment' on sidecar decision, say TT organisers
Race organisers say they won't be commenting further on the end of the sidecar racing at this year's TT.
Shop appeal after TT flag vanishes
A shop in Ramsey is appealing for the return of one of its official TT flags.
Thefts around TT Grandstand spark plea from police
Police are asking visitors to ensure their belongings are secure, after a spate of thefts at the TT Grandstand.
Crash closes stretch of Mountain Road until around 2pm
Police say part of the Mountain Road will be closed for at least another hour after a crash.
