Police say the Mountain Road is currently shut while emergency services deal with several incidents.
The entire route is closed, from Ramsey Hairpin to the Creg-Ny-Baa.
The announcement was made around 5.15pm this evening, Thursday, May 28.
No time has been given for when it's expected to re-open.
Coastguards and firefighters rescue boy from cliff
Coastguards and fire crews teamed up to save a boy who was hanging over a 36-foot cliff today.
12-seater ferry to Cumbria coming soon?
A new "minibus" ferry could soon be running from Cumbria to the Isle of Man.
Lifeboat launched to help fishing boat
Port St Mary's lifeboat crew was called to help a fishing boat earlier.
Smartmeter alert problem now fixed, says Manx Utilities
Manx Utilities says it's now solved problems that sent users false alerts about their smartmeter balance.
Merchant Navy Day marked this week
Merchant Navy Day will be marked on Island with a remembrance service for those who lost their lives at sea.
Filipino festival planned for Laxey
A huge celebration of the Island's Filipino community will take place in Laxey later this year.
Glen Maye requisition meeting scheduled
A requisition meeting will be held in Glen Maye next month.
Political satire is coming to the Gaiety Theatre in Douglas next week, just in time to poke fun at the general election.
