Police say the Mountain road could be shut until at least 7pm after a serious crash.
Officers say the incident means the route will be closed between Barrule Park and the Bungalow.
They say someone's suffered serious injuries in the crash.
No further details have yet been released.
Commissioners give Ramsey some TLC
Ramsey Commissioners say workers have been out and about this week making sure the town looks its best.
Suspected chemical munition means Derbyhaven remains closed
Experts from the UK will assess a chemical incident at Ronaldsway airport today.
Roads closed and bus routes changed for Parish Walk today
One of the Island's biggest annual sporting events is underway today.
Minister defends admission prices to MNH attractions
Enterprise Minister Tim Johnston says the cost of getting into the Island's historic sites is up to Manx National Heritage.
Thie Clag cafe up for rent
Could you run a business in the former Nurse's Home on Westmoreland Road?
Minimum wage changes on the way?
The government says it's planning changes to the way the minimum wage is calculated from next year.
Gas prices to rise by 5.3 per cent from July
Gas prices are due to rise by more than five per cent in less than a fortnight's time.
MP says UK is behind 'progressive' Isle of Man on assisted dying
A leading UK MP has admitted the country is behind progressive nations like the Isle of Man when it comes to assisted dying.
