Manx Care says it's top 10 drugs are anticoagulants, diabetes treatments and inhalers.
A Freedom of Information request asked for the 10 most-prescribed medicines along with their total cost last year.
In its response, Manx Care said it spent just under half a million pounds on prescriptions for Apixaban, which prevents blood clots.
The list also shows it spent £268,608 on 3,792 diabetes sensors.
Rural road to close for whole month this week
A country road in the South of the Island is to close for a month.
What help is there for using government online services?
What support is there for people outside Douglas who need help using government online services?
Weather warning for tomorrow
Ronaldsway Met Office has issued a yellow weather warning for coastal overtopping tomorrow.
Bad weather cancels two upcoming sailings
The Steam Packet Company says bad weather means two of its sailings this week have been cancelled.
Duo from Island finish 49-day Atlantic row
Two friends from the Island have spent 49 days rowing across the Atlantic for charity
Don't bring your own drone for show this week!
Flying your own drone at a professional show in Douglas this week could cost you £10,000.
Jurassic larks to return in May!
A roar-some charity event that sees runners dressed as dinosaurs will return to the Island in May.
Lord Street plans get go-ahead
Plans for a 12-storey multi-purpose development in Douglas have been given planning approval.
