The Island's branch of Next is set to close this summer.
It's because the store hasn't managed to come to an agreement to renew its lease with the landlord of the Strand Street premises.
The building is owned by Ramsey-based Kelproperties.
A total of 23 local jobs will be lost as a result.
Peel ready for bonfire and fireworks later
Government: "UK never told us about child murderer"
Farm shop's newest worker needs your name suggestions
Bus Vannin gives update on staffing problems and routes affected today
Toilets vandalised for fourth time in a month
Poppy gets fur-ever home after sparking rescue operation in Douglas
Council gets eight complaints about James Brown in six months
More bus staffing problems this weekend