Manx Utilities says motorists face six months of misery as it improves the capital's sewage system.
Work on a 23-week project on the Old Castletown Road will start on Thursday.
Kewaigue's pumping station will be replaced, and work will take place on the Old Castletown Road and Heron & Brearley brewery site.
There'll be a number of road closures and traffic restrictions between Thursday, April 3 and Wednesday, April 16.
One weekend sailing cancelled, others at risk because of weather
The Steam Packet says it's cancelled its Saturday afternoon sailing because of bad weather.
Politician questions risk of Easter meningitis outbreak
Could the Island face a meningitis outbreak over Easter?
Firefighters tackle flat fire down South
The fire and rescue service dealt with a flat fire in Castletown earlier this afternoon
Weather warning for storm Dave this weekend
Ronaldsway Met office has issued a yellow weather warning for severe gales as storm Dave will hit the Island.
Roads to close for music festival this weekend
Roads in Ramsey will be closed for a day this weekend for a Manx music and dance festival.
How long do mental health patients stay in Manannan Court?
How long do patients generally spend in the mental health ward during a crisis?
Could you take over this former restaurant?
A former restaurant in the Villa Marina Arcade is up for rent.
Framework of new Sea Services Agreement ready, says minister
The infrastructure minister says the basic framework of the new Sea Services Agreement with the Steam Packet has been agreed.
