Two people have been taken to hospital following a two-vehicle collision outside the Grandstand.
It comes following emergency services being called to Glencrutchery Road in Douglas just after 11.30am.
Firefighters cut free a casualty from each vehicle involved - who were then taken to Noble's Hospital.
The road will remain closed until 2:30pm while investigations are carried out.
Firefighters tackle flat fire down South
Weather warning for storm Dave this weekend
Roads to close for music festival this weekend
How long do mental health patients stay in Manannan Court?
Could you take over this former restaurant?
Framework of new Sea Services Agreement ready, says minister
Attorney General says he's stepping down
Road closures in two towns for running event this week