The Department of Infrastructure says the Tholt Y Will Road will be shut today as repair work takes place.
The route will be closed until 3.30pm, when it will reopen for the weekend before closing again at 9.30am on Monday.
The department says it needs to fix problems with the hairpin corners between the Tholt Y Will car park and Sulby Dam.
On Facebook, the DOI says access to properties in the valley will be via Sulby.
Bus services north and south face disruption later
Wildlife Trust unveils woodland plans
Deadline looms for by-election nominations
Biker in UK hospital after Mountain crash
Trial event closes roads in Peel and Ramsey
Requisition meeting for Garff voters
Castletown police station could be yours... for £250,000
Brewery advertising for operator for landmark Laxey pub