Year 9 pupils at St Ninian's High School are being asked to work from home today (21 March).
In a letter addressed to parents and carers, the school says it's down to 'extremely high levels' of staff absence.
All other year groups are currently unaffected.
The school says the situation will be assessed again today to see if alternative arrangements are needed for the rest of the week.
Attorney General says he's stepping down
Road closures in two towns for running event this week
Six weekend ferry crossings could face disruption
President of Tynwald announces retirement
Police close Mountain road
Fuel firm says "fingers crossed" for calmer energy costs
Ring doorbells will need data protection registration - but shouldn't cost you money
Hospice UK head calls Island cuts "cack-handed" ministerial muddle