The Department of Infrastructure says seven bus services may be called off today.
Bus Vannin took to Facebook to update people about ongoing problems caused by short-staffing and illness.
Routes from Douglas to Peel, Port Erin, Colby, Ballachrink and Port St Mary may all face cancellation.
The potential problems are this afternoon and evening, from 1pm to just after 7.30pm.
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Manx Care doctor survey to be discussed by Tynwald
Weather warning for snow tonight
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Warning issued over icy roads
High ground could see 4 inches of snow on Saturday night