Manx Care says it's top 10 drugs are anticoagulants, diabetes treatments and inhalers.
A Freedom of Information request asked for the 10 most-prescribed medicines along with their total cost last year.
In its response, Manx Care said it spent just under half a million pounds on prescriptions for Apixaban, which prevents blood clots.
The list also shows it spent £268,608 on 3,792 diabetes sensors.
Castletown police station could be yours... for £250,000
Fancy owning a landmark building in the south of the Island?
Brewery advertising for operator for landmark Laxey pub
Could you run one of Laxey's best-known pubs?
Hospice cafe reopens next week after refurb
A much-loved café will be throwing open its doors again next week.
Another one bites the gust - as Ramsey rocks cancelled
A huge live music event in Ramsey this weekend has been cancelled.
Mountain Road closed again after crash
The Mountain Road is currently closed after a crash.
Merchant Navy Day to be marked with memorial service
Merchant Navy Day will be marked on Island with a remembrance service for those who lost their lives at sea.
Fundraiser launched for injured MGP rider
A fundraiser's been launched to raise money for a Czech rider who was injured during the MGP.
Noel back in the saddle after handy pub pumping leaves him smiling
Noel Edmonds has thanked a pub in the north of the Island for helping out when he felt a little deflated.
