Onchan MHK Julie Edge wants to know how many Island-based retailers register their online sales in the UK to use Stripe for payments.
In its reply, Enterprise Minister Tim Johnston said the Department doesn't have data on numbers or the economic impact.
He added any tax loss is likely minimal, but limited access to payment providers may increase business costs and restrict opportunities.
Stripe isn't currently available on the Island, but the government offers a Global Digital Access initiative, helping businesses with Etsy Payments, Google App Development access and PayPal.
Repairs on Peel Power Station to get underway
Manx Care doctor survey to be discussed by Tynwald
Weather warning for snow tonight
MHK queries safety at primary school in Ballabeg
Gales put two ferry sailings at risk tonight
Should the Island throw a birthday party for Barry Gibb?
Warning issued over icy roads
High ground could see 4 inches of snow on Saturday night