Airline Loganair says it'll run flights to Heathrow and London City airports from April.
Services between Heathrow and Ronaldsway will start on Tuesday, May 3 and tickets will go on sale next week.
Chamber of Commerce chief executive Rebecca George says the organisation's very pleased to see the return of flights to central London.
Loganair previously scrapped the route in July last year after the government ended subsidies introduced when borders closed because of coronavirus.
What would be the impact of raising the income tax threshold?
How much would it cost the government to increase the income tax threshold?
Nominations open for Manx cultural hero awards
Do you know a Manx cultural hero who should be celebrated?
Passport and immigration public counters to temporarily close
The Government Offices passport, immigration and nationality public counters will be temporarily closed next week.
Overnight delay means today's sailings will set off late
A number of Steam Packet sailings will be setting off later than scheduled today, Saturday, November 1.
Fireworks displays to kick off with event tonight
Fireworks displays are set to go off with a bang around the Island, starting tonight.
Second night of police roadside car checks finds less defects
Police say their second round of winter car checks found less defects than the first night.
Society appeals for help about traditional gypsy caravans on the Island
Do you know of any traditional gypsy caravans on the Island?
Government issues bird flu warning after infected buzzard found
The government's warning people not to touch sick or dead birds after a wild buzzard which died of bird flu was found in a garden near Bride.
