The Mountain Road has shut this morning after a crash.
Police say the route is closed between the Ramsey Hairpin and the Bungalow after an incident earlier involving one vehicle.
It happened just after 7am.
Drivers are being advised to use alternate routes.
Visa fraudster convicted in Isle of Man immigration scam
Crowds gather for Maccies re-opening after £1.6m upgrade
MHK questions wages of 1,500 extra workers
Manxman sailings cancelled today
New parent employment rights to start this Saturday
70% of cars fail police winter roadside checks
Festival of Remembrance at the Villa next month
Planning fireworks? Let the airport know