Ballafletcher Road has now re-opened following a chemical spill yesterday.
The area near the Vehicle Testing Centre was shut for hours yesterday afternoon as a result.
Residents in Douglas were asked to stay inside with windows and doors closed as a precautionary measure.
However, Police have now confirmed the route is clear and have thanked the public for their patience during the lengthy closure.
Biker in UK hospital after Mountain crash
Trial event closes roads in Peel and Ramsey
Castletown police station could be yours... for £250,000
Brewery advertising for operator for landmark Laxey pub
Hospice cafe reopens next week after refurb
Another one bites the gust - as Ramsey rocks cancelled
Mountain Road closed again after crash
Merchant Navy Day to be marked with memorial service