The Department of Infrastructure says 19 bus services are at risk of cancellation today.
Bus Vannin says routes between Douglas and Port Erin, Ramsey, Onchan and Willaston are at risk.
It's after weeks of disruption because of driver shortages and illness.
Today's problems include a number of commuter buses between 5pm and 6pm.
How will Manx Care reduce the number of negligence claims?
Manx Language Festival to be held next week
Manxman sailings in doubt from tomorrow
Car falls down steep bank on Mountain Road
Panic over - Mcdonald's reopens at 11am tomorrow
Police say beat it to cars illegally parked during MJ tribute act
No dedicated prostate cancer screening programme, despite over 1,200 referrals
Minister says GP waiting times have improved, but delays still impact A&E