A huge 24-hour event will see hundreds of people taking part this weekend.
The Relay for Life Isle Of Man will be held at the National Sports Centre from midday on Saturday, August 26, until midday on Sunday, August 27.
The fundraiser supports the work of Cancer Research UK in an overnight celebration and tribute to those who suffer with the disease.
Organiser Lynn Bell explains what it's all about:
'Incredible' M&S team marks 150 years of collective service
Coastguards complete two rescues in a day
Space to bring 90's vibes to the 'Neighbourhood'
Noble’s Private Patients’ Unit reopening later this year for some procedures
Ballasalla roundabout could be completed next year
Two more schemes backed by government fund
Island to get Bikesafe scheme for first time
Jurby Junk's Stella dies aged 90