A huge 24-hour event will see hundreds of people taking part this weekend.
The Relay for Life Isle Of Man will be held at the National Sports Centre from midday on Saturday, August 26, until midday on Sunday, August 27.
The fundraiser supports the work of Cancer Research UK in an overnight celebration and tribute to those who suffer with the disease.
Organiser Lynn Bell explains what it's all about:
Repairs on Peel Power Station to get underway
Manx Care doctor survey to be discussed by Tynwald
Weather warning for snow tonight
MHK queries safety at primary school in Ballabeg
Gales put two ferry sailings at risk tonight
Should the Island throw a birthday party for Barry Gibb?
Warning issued over icy roads
High ground could see 4 inches of snow on Saturday night