The Department of Infrastructure says 10 buses face cancellation today.
Services between Douglas and Peel, Niarbyl, Willaston, Ballchrink and Farmhill could all be affected.
Bus Vannin says the affected routes are facing problems from just after 2pm until just after 11pm tonight.
It's after more than a month of problems caused by short staffing and sickness.
Repairs on Peel Power Station to get underway
Manx Care doctor survey to be discussed by Tynwald
Weather warning for snow tonight
MHK queries safety at primary school in Ballabeg
Gales put two ferry sailings at risk tonight
Should the Island throw a birthday party for Barry Gibb?
Warning issued over icy roads
High ground could see 4 inches of snow on Saturday night