Ramsey Cottage Hospital will close when its water is turned off next week.
The Minor Injuries and Illnesses Unit will close at 6pm on Thursday, March 27.
Manx Utilities will be carrying out planned work.
Manx Care says anyone with minor injuries or illnesses after 5.30pm should go to Noble's Hospital.
New amber warning issued for tonight's storm
Police appeal over theft of building materials
One of capital's oldest buildings may become housing
New NHS safety rule to be brought in on Island
Two city streets to shut for over six months
Revamp of airport terminal planned, says DOI
Four ferries now listed as cancelled today
One weekend sailing cancelled, others at risk because of weather