The Mountain Road is closed until further notice.
Police say it's due to poor driving conditions, as snow, sleet and hail fall across the Island.
There's also been a crash at Whitebridge in Onchan which has resulted in the road being blocked.
Meanwhile, several vehicles are also stuck due to snow and ice.
Authorities are asking the public to only travel if your journey is essential to help relieve pressure on the emergency services.
How much has been spent on carbon literacy training?
Gov made no assessment before apprentice scheme changes
Government strategy to promote local food under spotlight
Local man to run famous marathon for Children's Centre
Are there supply issues at the meat plant?
What's the target patient to GP ratio?
Plans for new high school to be discussed
Katie Hopkins confirms Island return