Africa House, on Woodbourne Road in Douglas is on fire.
In a post on social media, police have confirmed Emergency Services are at the scene.
People are asked to avoid the area whilst a section of Woodbourne Road is currently closed between the junction of Albany road and York road traffic lights.
Laxey's La Mona Lisa changes hands after 22 years
The owners of a long-running Italian restaurant are handing over the reins.
Cruise ship to visit the Island today
A cruise ship carrying more than 1,000 people is due to visit the Island's capital today.
MHK says minister could have avoided blushes with earlier warning
Arbory, Castletown and Malew MHK Jason Moorhouse says his blushes could have been spared if a minister had contacted him earlier about a question in the House of Keys.
Bad weather means two ferry crossings cancelled
Two ferry sailings have been called off in the face of bad weather tonight.
Commissioner hits out at "nuisance" campervans
Are camper vans becoming a problem in Onchan?
Livestock worrying consultation ends this week
There are just days left to air your views about dog attacks on farm animals.
Warning over possible ferry disruption tonight
Two ferry sailings are at risk of disruption tonight.
Department told to provide new FOI response to Visit Isle of Man query
The Department for Enterprise will have to give a new answer to a Freedom of Information request after an appeal to the Island's information commissioner.
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